Documentation

pyrovelocity is a Bayesian, generative, and multivariate RNA velocity model to estimate uncertainty in predictions of future cell states from minimal models approximating splicing dynamics. This approach models raw sequencing counts with synchronized cell time across all expressed genes to provide quantifiable information on cell fate choice and developmental trajectory dynamics.

Features

• Probabilistic modeling of RNA velocity

• Direct modeling of raw spliced and unspliced read counts

• Diagnostic analyses and visualizations of model uncertainty

• Synchronized cell time estimation across genes

• Multivariate modeling of gene expression and velocity prediction

Indices and tables

• Index

• Module Index